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Two key US Republican senators said a Tuesday briefing by the CIA's director only strengthened their conviction that Saudi Arabia's crown prince directed the murder of journalist Jamal Khashoggi.

The Istanbul chief prosecutor's Tuesday court application says there is "strong suspicion" the two aides were involved in planning the killing.

The ambassador is the brother of Saudi Crown Prince Mohammed bin Salman, whose alleged role in ordering the murder is at the heart of a burning controversy in the United States and across the world.

"I talked directly to the prince in Buenos Aires, telling him that we need better answers on what happened to Khashoggi and who is responsible for it", he said.

Following a private Central Intelligence Agency briefing on Tuesday, republican senator Lindsey Graham said he had "high confidence" the Saudi leader had a role in the murder and added "you have to be wilfully blind" to disagree.

After the hearing, Senator Lindsey Graham told reporters that there is zero chance the crown prince wasn't involved. Rand Paul is up in arms.

There are several proposals in the works, including freezes on all U.S. arms sales to Riyadh and tightening sanctions on those involved in Khashoggi's murder.

"Before this briefing, I was convinced that we had to take steps on the war in Yemen and I believe that we had to take steps on the Saudis", Menendez said.

Many reports claim the actor, 58, is filming a documentary on Jamal Khashoggi, the Saudi journalist who was murdered in the Saudi consulate in Turkey.

A team of 15 Saudi agents, allegedly sent by Qahtani, assassinated Khashoggi at the Saudi consulate in Istanbul.

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The Saudi government went into damage control mode, with a spokesperson for the Saudi Embassy, Fatimah Baeshen, saying the kingdom maintains its "steadfast" commitment to the US-Saudi relationship and does "categorically reject" accusations linking the prince to the killing.

Khalid had flown back to Saudi Arabia shortly after the murder of journalist Jamal Khashoggi inside the Saudi consulate in Istanbul in early October, just as global outrage and pressure was mounting on Saudi leaders over the killing.

Saudi Arabia has detained 21 people and says it is seeking the death penalty for five.

"The prosecution's move to issue arrest warrants for Asiri and Qahtani reflects the view that the Saudi authorities won't take formal action against those individuals", one of the Turkish officials said. "His status as such remains unchanged", the official said.

The official, who did not wish to be named, also suggested there could be more arrest warrants sought by the prosecutor.

She said her office doesn't have the mandate to conduct a criminal investigation, however.

Cavusoglu also criticised the lack of evidence given to Turkey by Riyadh as he urged the kingdom to be "transparent".

Many Democrats want a "straight up or down vote" on a war powers resolution to end all USA support for the Saudi coalition in Yemen, without amendments.

Two-time Oscar victor Sean Penn was in Istanbul on Wednesday filming a documentary about the murder, Anadolu reported, sharing images of the American actor outside the consulate.