Pence warned Saturday that United States sanctions and pressure on China would remain in place until Beijing reforms its trade practices.
His comments come a day after President Donald Trump told reporters he was confident a deal between China and the USA "will be made".
United States Vice-President Mike Pence told a gathering of business leaders at the Asia Pacific Economic Co-operation summit that there would be no backing down from tariffs until China changed its ways.
"We've put tariffs on $250 billion in Chinese goods and that number could more than double", he told CEOs from around the region.
The anti-protectionism sentiment was also echoed by the Chinese president, Xi Jinping.
"The rules made should not be followed or bent as one sees fit and they should not be applied with double standards for selfish agendas", Xi said.
The two countries have been engaged in a tit-for-tat trade war this year. He announced a Indo-Pacific Transparency Fund, in which the US, Australia and Japan would partner to assist infrastructure funding.
In a major speech, Xi also stressed that there would be no winners from a trade war or a new cold war amid increasing rivalry between the world's top two economies. "'America First' is not America alone", he insisted, before launching into a stinging attack on China, mocking the BRI as a "Constricting Belt or One-Way Road", and warning gathered leaders "do not accept foreign debt that could compromise your sovereignty".More news: More heavy rain for Tuesday
"It is not created to serve any hidden geopolitical agenda, it is not targeted against anyone and it does not exclude anyone. nor is it a trap as some people have labelled it", he said.
Local media covering the arrivals in Port Moresby have been refused entry while the National Airport Corporation and protocol officers allowed the global media through.
"We have taken decisive action to address our imbalance with China", Mr. Pence declared. President Xi was all about [US President] Donald Trump's tariffs.
Thomas added that the fringe events at the summit provided more insight into the wider geopolitical aims of the participants, with China looking to boost support for its position on Taiwan. "Which direction should we choose?"
"So, just [as] with aid and investment, food and drinks receptions come with strings attached".
"I keep on telling people that to make a vehicle, you have to make 4,000 different components, and then put them together".
President Trump was not at the summit, but will meet with Jinping in at the G-20 summit in Argentina that begins later this month, Reuters reported.
China has demanded the US stop deploying ships and military aircraft close to its man-made islands in the disputed waters after American and Chinese ships almost collided near a contested reef in September.