Drummond fired back by calling out Embiid's injury history and inability to play in back-to-back games for most of his career.
Griffin faked a handoff on the final play and drove the lane for the basket, getting fouled by Robert Covington.
Blake Griffin had his first career 50-point game in a win over the Sixers on Tuesday, which included five 3-pointers and a game-winning and-1 in overtime.
He scored 22 points in the second quarter and had 28 in the half, despite missing his first six free throws.
Griffin was dribbling in transition in the second quarter in Detroit and fooled Philly with a fake pass.More news: Huh: Man Groped a Woman on an Airplane...And Then Blamed Trump?
Then, down the stretch of regulation, the teams traded the lead six times, with three ties. The Milwaukee Bucks did the bulk of their damage in the 2nd quarter, posting an astounding 49 points during the 12-minute interval, with the momentum riding high on their shoulders.
After the game, Embiid spoke about the incident, saying that the refs told the two players to knock it off with the cheap shots and trash talk, and the next one would earn a technical foul.
Drummond held his palms in the air after the foul call, while Embiid, who had gone to the floor, got up and gesticulated to the official to throw Drummond out of the game.
The Pistons' big man was quickly ejected, and Embiid got up and demonstratively gestured as if throwing Drummond out of the game, like a baseball umpire.
Pistons: Thursday they host Cleveland, which will be on a back-to-back after playing host to Brooklyn on Wednesday.