The tournament is certainly going to be a lot quieter without El Diego.
For Argentina, the man to watch is once again Lionel Messi.
Messi played at his first World Cup in 2006, helping the team reach the quarter-finals.
"It was a insane game where we did not start well, we recovered and we turned it around, but the equalising goal from them hurt us a lot".
Sampaoli says Argentina will "play with a knife between their teeth" when they take on France, and he is expected to make a significant change to the side's attacking line-up. Portugal defender Pepe made Uruguay pay for sitting back when he leapt unmarked to head in a cross from Raphael Guerreiro following a short corner to level the match at 1-1 in the 55th minute. "I won't decide my future today".More news: Trump to Harley-Davidson: 'We won’t forget, and neither will your customers'
That was the first goal the twice World Cup champions had conceded in the tournament in Russian Federation, but it took Cavani only seven minutes to put them back ahead at the packed Fisht Stadium overlooking the Black Sea. "We have a young and ambitious squad", he said.
Season after season, Messi is still a gravity-defying magician with the right assistants, while Ronaldo must be lauded for the diligence he has shown sculpting everything - from his physique to his pace, power and precision with the ball.
Ronaldo finishes his fourth World Cup campaign with four goals, while Messi notched just the one in what was also his fourth, scoring the opener in Argentina's huge group stage win over Nigeria in Saint Petersburg.
Ronaldo had the opportunity to stake his claim as the GOAT at the World Cup following Messi's elimination but he, too, is being sent home after Portugal lost 2-1 to Uruguay courtesy of a dazzling Edinson Cavani display. "That is our best chance against any adversary, and we know that France will be very tough indeed".
After Uruguay clinched victory to set up a last-eight showdown with France, Cavani told A Bola: "It's very exciting".