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In a phone conversation with German Chancellor Angela Merkel a day after a series of Israeli strikes, Iran's President Hassan Rouhani said his country is not interested in starting new conflicts in the region.

"Rather, Europe needs to take its fate into its own hands".

Earlier in the week, President Donald Trump withdrew the United States from the 2015 deal.

Merkel acknowledged global concerns over Iran's influence in Syria, Iraq and Yemen, and its ballistic missile program, but underlined that these issues should be discussed with Tehran, without abandoning the nuclear deal. "That's the task for the future".

Germany must wean itself off the "fetish" of fiscal conservatism if it has ambitions to become a leading force for European renewal, French President Emmanuel Macron said on Thursday. "And it will be existentially necessary to make progress here because the nature of conflicts has completely changed since the end of the Cold War".

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But they are at odds on economics and finance, with Merkel reluctant to take steps - such as setting up a euro zone budget - that might lead to Germany carrying greater liability for other euro zone countries' problems. "The escalations of the past few hours show us that it is truly about war and peace".

Israel has said its strikes in Syria were in response to the attacks against the Golan Heights, which it blamed on Iran.

Both Macron and Merkel spoke with Trump about maintaining the deal in the weeks leading up to his announcement, even going so far as to lay out a four-point plan for restructuring the agreement as Trump said he wished to do.

Macron, who received the Charlemagne award at Thursday's event, echoed many of Merkel's points in pushing for a European foreign and defense policy.