City are one goal short of the Premier League record of 103 set by Chelsea in 2009-10.
"I'm happy we will receive the Premier League trophy and (have) the chance to be the best team in history in England, with the most points", Guardiola said.
The win means that the Citizens need just one win to record the most Premier League victories ever recorded in one season.
Southampton's downfall this season has been surprising as they appeared to become a regular feature in the Premier League, especially considering their strong cup displays in the past two years.
"They make the pitch very big, they've got players in positions you'd hope you wouldn't be and they're slick, they're quick and that's why they're champions". We will have to play good to break the record. Gunners midfielder Granit Xhaka had endured a torrid first half, but the Swiss global nicked the ball in midfield to find Henrikh Mkhitaryan, who advanced on goal and his low effort from the edge of the area rather crawled past David De Gea.More news: Activists Send Lawyers To Border To Coach 'Caravan' Asylum Seekers
West Ham face Leicester City at the King Power Stadium on Saturday. Last weekend's 5-0 thrashing of Swansea showed the champions hadn't taken their eye off the ball, even if goalkeeper Ederson's unsuccessful campaign to take a penalty was a sign of the relaxed mood in the City camp.
However, Noble stressed the importance of points from their last three games, two of them being at home, against Manchester United and Everton, which he believes will define their season as they fight against being pulled into the drop zone.
The West Ham fans' joy was short-lived, however, as City upped the ante after the break.
Bravo would struggle badly himself last season as City finished third in the table.