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For his part, Muallem briefed the Iranian official on the latest political developments in Syria, saying that "we appreciate the valuable support of the Islamic Republic of Iran for Syria in all fields".

More recently, Israel's leaders, including Prime Minister Benjamin Netanyahu, have also spoken about preventing their enemy Iran from establishing a permanent presence in Syria and from creating a corridor of Iranian influence spanning from Tehran to the Mediterranean Sea.

On April 9, a massive missile strike was delivered on the T-4 airfield in the Syrian province of Homs. The attack killed at least 14 people. This is likely because Israel has regularly attacked Syria for years now, without such a pretext.

Netanyahu, Defense Minister Avigdor Lieberman, Israel's armed forces chief and the head of military intelligence met on Wednesday before a security cabinet session got under way, government officials said.

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"The Iranians are determined to base themselves in Syria", he told the Army Radio station. "They are our strategic partner, and our defense establishment is in constant contact with them", Elkin said. "It's possible Iran will attempt a response against us".

Also on Tuesday, Israeli Internal Security Minister Gilad Erdan told the Hebrew-language Ynet news site that Israel's ties with Russian Federation are "very important", but "we have to adhere to our policy and not allow the Iranian enemy to cross our red lines". But Israel has made clear that it will take action to prevent Hezbollah, a Lebanese Shiite militia backed by Iran, from using Syria as a springboard for attacks against Israel and to block Iran from transferring weapons to Hezbollah in Lebanon. "It only remains for it to operate militarily and independently to curb the Iranian foothold in Syria, in the hope that its military activity will not devolve into an overall confrontation".

Amos Yadlin, a former Israeli military intelligence chief, wrote on Twitter that "the Iranians will probably respond to the strike attributed to Israel, even if not immediately".