Youngs was injured less than 10 minutes into his 56th start for England, which overtook Matt Dawson's record of most starts for an England scrum-half.
Italy were not finished yet, Bellini squeezing over in the left corner to finish another fluent move just before the hour-mark, but the nippy Ford scooted over after he was fed on the inside by Farrell and Simmonds rounded off a superb Six Nations bow by turning on the after-burners to go under the posts.
"We're in this tournament to win it", said Jones.
British and Irish Lions midfielder Te'o, a powerful ball-carrier, has displaced Jonathan Joseph, more of a traditional "running" centre, in the side picked by Australian coach Eddie Jones after recovering from a severe ankle injury that ruled him out of England's November series. "A lot of the boys here were saying as well how quick he is, but he's got a big backside so that's where the power comes from". "We want to be brutal and absolutely ruthless and that's the team to do it". Jones was having none of it, but it can not be denied that the most eye-catching performance of this ultimately predictable victory - England's self-styled hunters eventually feasting on their Italian prey - was that of Sam Simmonds, the newest member of this side.
Italy mentor Conor O'Shea has named a side including a few unpracticed players.
Dylan Hartley, the captain, is also demanding England flex their muscles.
However, this year's Six Nations opener at the Stadio Olimpico was far from it as the reigning champions' defensive frailties were exposed by a country determined to maintain their position in the tournament.
Maro Itoje starts in the second row alongside Joe Launchbury. And that all starts on Sunday. "We always knew it was going to be a tough game, they played exceptionally well and full credit to Italy ... it was a good tough game of rugby and we ran away with it in the end".More news: Driver opens fire on African migrants in Italian city of Macerata
Maro Itoje is not happy against Samoa at Twickenham Stadium in November previous year. I don't think we've scrummed as well as that in the time I've been in charge of England.
Flankers Renato Giammarioli and Sebastian Negri have three games between them, while midfield organization Tommaso Castello and Tommaso Boni have a sum of only 13.
By selecting a team featuring seven Six Nations debutants, Italy coach O'Shea has a group ofr players who have not been worn down by repeated failure.
But whether the newcomers add fresh self-belief remains to be seen.
'They are shaping up nicely with 22 wins in 23 games which is quite a feat and they're constantly evolving, developing and gaining more belief.
Nevertheless, the scoreline will make upsetting reading to a nation struggling to cope with a first omission from the football World Cup later this year.
Italy wilted in the closing stages after putting so much effort in and fit-again replacement Nowell helped himself to a seventh try three minutes from time, Farrell failing to convert but England finishing the contest in style with a clash against Wales to come next Saturday.