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This indicates that they had developed a condition called "compensated hypogonadism", which happens when testosterone production is reduced, but the body is able to compensate by increasing LH levels, the researchers said.

"Ibuprofen works really well as a painkiller and fever-reducing medicine, so there are of course a number of cases where taking it is sensible", he says. In the men receiving ibuprofen, levels of luteinizing hormone were up, and the ratio of testosterone to luteinizing hormone dropped. Although it is massively taken by people from all over the world it can cause stomach bleedings, ulcers and it increases the risk of having a stroke or heart attack. Fourteen of them took a daily dosage of ibuprofen that many professional and amateur athletes take: 600 milligrams twice a day.

Regularly taking common over-the-counter painkillers may contribute to male infertility, a problem that affects roughly 7% of American men, according to new research.

Researchers came to this somewhat disturbing conclusion after splitting 31 male test subjects between the ages of 18 and 35 into two groups; they gave one group ibuprofen, and the other group a placebo.

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The men who took ibuprofen during that time had a condition called compensated hypogonadism, which can lead to fertility issues and erectile dysfunction, according to the study. Essentially testosterone levels were normal but the men in the ibuprofen group had higher amounts of luteinizing hormone, which stimulates testosterone production.

The adverse effects in the study weren't permanent.

The good news is that the problems required multiple weeks of constant ibuprofen use, so there's no indication that handling the odd muscle ache or hangover with ibuprofen will cause problems. It didn't take long - just two weeks - for the drug to disrupt the hormonal balance and rate of testosterone production of these men. Every pregnant woman should consult or doctor before taking any of these three substances.

While it is certain that the hormonal effects in the study participants who used ibuprofen for only a short time are reversible, as CBS reported, it's unknown whether this is also true after long-term ibuprofen use, study co-author Bernard Jegou, director of the Institute of Research in Environmental and Occupational Health in France, told CNN.


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