On the other hand, The Disaster Artist - James Franco's well-received making-of film about The Room - was indeed nominated for Golden Globes for both Best Picture (musical or comedy) and Best Actor for Franco's performance- an award for which Franco won the Golden Globe.
Franco, the son of parents who met while attending Stanford University, is a 1996 graduate of Palo Alto High School, where he got his acting start by appearing in school stage plays.
Franco opens his speech by quoting Wiseau's reference to the Golden Globes two decades ago, and his lack of an invite to the show as a motivation to make "The Room".More news: Caitlyn Jenner doesn't trust Kardashians
Franco made the big toast of the night, but all of the men went around the room to address the group, Hammer added when speaking to Seacrest on the red carpet.
Franco was the second actor with Bay Area ties to win Sunday night.
His one previous Oscar nomination came in 2011 for "127 Hours". Wiseau gained infamy for creating 2003's "The Room", a cult classic that came to be known as "the Citizen Kane of bad movies".
"I used to want my own Coen brother, someone to collaborate with", James Franco said.
Receiving a somewhat chillier reception was Tonya Harding, the champion figure skater who was the subject of this year's I, Tonya and linked to the 1994 attack on fellow skater Nancy Kerrigan.